Ment
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The main thing is to introduce a limit on the stats, so that there aren't any characters with 45 strength and everything else at 15, or introduce a link between the stats, so that to increase strength to 30, you first need to increase endurance to 20, or all other stats, so that there isn't a big gap between them.
You can also introduce racial restrictions, as is often the case in games.
As I've said many times, you're looking at the stats in isolation from the rest of the system.
It's difficult for me to imagine abilities tied to endurance; there will probably be very few of them.