Yes, young man, I don't play as a Witch Hunter – this combination of skills doesn't inspire me. First Strike is one of the most useful spells, practically for any monster, but it will be even more useful against Chaos Dragons with their fear ability. Of course, you need to be careful with Chaos Dragons so as not to harm your own units and lose fewer of them.
Why use First Strike against Chaos Dragons that don't have First Strike? They don't attack without retaliation; they just force you to retreat. And if the Chaos Dragons have First Strike, then Pikemen, Dragon Golems, and Goblin Knights with the ability to ignore First Strike are enough to prevent them from attacking first.
You also need to know how to deal with Hydras so that you don't attack them one at a time