Nestle
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In the campaign, I developed my reputation based on my understanding of the factions' morality:
Necropolis - blood, Haven - tears, Sanctuary - tears, Inferno - blood.
For the same reasons, I also ended up with the same results. Nastya and Kirill - in blood, and Anton and Irina - in tears. I haven't played with orcs yet, but I think I'll develop Sandor in blood, as orcs are associated with blood.
Although, in my opinion, it's easier to develop in tears.