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According to my calculations (though I might be wrong, I checked recently), different skills for magic resistance and artifacts don't have any significant impact on the damage dealt by the Warlock's Armageddon spell. I believe it doesn't decrease at all. There is the Staff of Sar-Iss to counter resistance. However, I've been thinking and came up with a way to easily defeat such a tricky opponent (but I won't tell you, figure it out yourself).
