Study the template scheme carefully. There is usually a way to reach your opponent through a shared secondary town!
And breaking a Grand Order on the second week is very much possible.
Seriously, no matter how strong the player is, breaking a Grand Order on the 2nd week is possible in approximately 1 out of 20-30 cases, and on the 3rd week, approximately in 1 out of 5-10 cases (at least without losing almost all your troops). This is a fact, and isolated examples don't count.
Added after 4 minutes
lol. What can they counter with against a Deemer dealing 3x250 damage from Meteor Shower on level 124?