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Skills are, in my opinion, equivalent.
We tested: Tazar, level 20, with 10-10-1-1 stats and 1 Archangel, against Kreg with the same parameters, level, and Archangel; they deal the same damage to each other!!!
But from the point of view of fighting neutrals, defense will be more reliable.
For example, if you give a neutral unit Defense and it runs to our archers... There are many different situations.
And D or Space can be very decisive! Especially when you don't kill a unit in one hit and it doesn't kill you!!