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It’s tough to play against Inferno, especially with dark magic, in my opinion.
Nightmares and dogs reach the orcs, disrupting their rage... If there’s a tactic with a speed aura or boots that increase speed, then not only they will reach, but others too. Imps will steal mana, and the orc will have trouble with spells. And the hero himself will weaken the army with spells, and if he has enough mana to cast vampirism and/or mind control, the orc will be in a very bad situation.
In general, it’s difficult against races with high initiative. However, orcs compensate for their average initiative with leadership, which is almost always leveled up.
Defense isn’t a big problem for orcs due to their high attack. The damage won’t be insignificant; races with poor defense will suffer greatly.