Horizon of Darkness

Actually, it is... but the question was about poison, disease, slowing, etc.

For now, I'll sketch out a concept.

The character is a human who has evolved a bit differently (most likely, I'll play as a female, but that's not the point). Blind from birth, but uses echolocation incredibly well. An albino with thin, translucent skin, completely white eyes, looks sickly and a bit creepy, but still passes as a human, just a very sickly one.

+ Protection (or complete immunity) from critical hits, can detect ambushes, excellently developed hearing and sense of touch, immune to blindness, doesn't care about the level of illumination, goes into the darkest caves without a torch and is fine.
- For obvious reasons, cannot write or read, the range of perception is limited (how much can be covered with echolocation), the worldview is quite specific and abstract.

I think such a character would be a good agile swordsman, rogue, and poisoner, bringing back some old-school vibes.

Of course, the buffs will go into the slots for passive perks. The question is - how much of this can be crammed into the slots, considering that the character also has debuffs.

most likely I'll play as a female

would be a good agile swordsman, rogue, and poisoner