There are no more quests from the main factions (except for eliminating each other). My reputation with humans is 96 (I don't know where to get the rest - I checked, I completed everything for humans except the final quest). I played as humans (but I got 100% with the elves).
I definitely won't be able to complete Uoroku's tasks (I helped the spy), but if I play as orcs later, it's absolutely necessary to know what the "ruins" are and what the artifact is.
P.S. The map is cleared (the ruined castle on the mountain is not active).